Systems Biology - MSc Immunology and Global Health
This lecture gives an overview of systems biology with an
introduction to quantitative and dynamical probelms and
approaches in biology as well as to mathematical modelling
of biochemical reaction systems, from genetic regulation
over signal transduction to whole organ/organisms.
Recommended literature
- Alex Mogilner, Roy Wollman & Wallace F. Marshall:
Quantitative
Modeling in Cell Biology: What Is It Good for?
Developmental Cell 11(3) 279-287, Sept. 2006.
- Barbara Di Ventura, Caroline Lemerle, Konstantinos
Michalodimitrakis & Luis Serrano:
From in
vivo to in silico biology and back,
Nature 443(7111) 527-533, Oct. 2006.
- Denis Noble:
Systems
Biology and the Heart,
Biosystems 83 (2-3) 75-80, Feb.-Mar. 2006.
- Alan Garny, Denis Noble & Peter Kohl:
Dimensionality
in cardiac modelling,
Progress in Biophysics and Molecular Biology
87 (1) 47-66, Jan. 2005.
- Edmund J. Crampin, Matthew Halstead, Peter Hunter, Poul
Nielsen, Denis Noble, Nicolas Smith & Merryn Tawhai:
Computational
physiology and the physiome project,
Experimental Physiology 89(1) 1-26, Jan. 2004.
- Ulisses M Braga-Neto & Ernesto T. A Marques, Jr:
From
Functional Genomics to Functional Immunomics: New
Challenges, Old Problems, Big Rewards,
PLoS Comput Biol. 2(7) e81, July 2006.
- Christian V. Forst:
Host-pathogen
systems biology,
Drug Discovery Today
11 (5-6) 220-227, March 2006
- Edda Klipp, Ralf Herwig, Axel Kowald, Christoph
Wierling & Hans Lehrach:
Systems Biology in Practice - Concepts, Implementation
and Application,
Wiley-VCH, 1st Edition, February 2005.
- Zoltan Szallasi, Jörg Stelling &
Vipul Periwal (editors):
System modeling in cellular biology: From concepts to
nuts and bolts,
MIT Press, 1st Edition, April 2006.
- Stephen P. Ellner & John Guckenheimer:
Dynamic Models in Biology,
Princeton University Press, 1st Edition, April 2006.
Eric Bullinger, 19 October 2006
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